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. 2011 May 18;6(5):e19444. doi: 10.1371/journal.pone.0019444

Figure 3. Successfully ageing (class “A”) old worms have higher mtDNA copy number than animals showing motility defects.

Figure 3

Comparison of mtDNA copy number in JK1107 worms from the same cohort (identical genotype and environment) scored at the same age (day 12) but found to be in different motility classes. Graph shows scatter and median of individual worm copy number because data are not normally distributed. Class “A” worms have statistically significantly higher mtDNA copy number (median 210,000 vs. 170,000 copies) than class “B” and “C” animals (P<0.001, Mann-Whitney test). The n-numbers for class “A” and “B”/”C” were 55 and 52 respectively, although we typically found very few class “C” worms on day 12.