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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Mol Cell Biochem. 2011 Feb 27;352(1-2):143–154. doi: 10.1007/s11010-011-0748-y

Table 2.

Uptake studies in stable recombinant HEK cell lines

Substrate Uptake by transfectants (dpm/µg)

Vector BOCT1 BOCT2 OCT1 OCTN2
MPP+ 9.3 ± 0.8 9.9 ± 0.7 9.0 ± 0.4 372 ± 12* 16.9 ± 0.4
TEA 117 ± 3.9 112 ± 1.7 126 ± 7.5 223 ± 6.4* 112 ± 7.2
Carnitine 186 ± 16 209 ± 6.1 192 ± 9.6 241 ± 6.7 2,288 ± 84*
Choline 271 ± 5.2 265 ± 7.0 272 ± 20 510 ± 8.8* 297 ± 47
Histamine 24.4 ± 7.7 9.1 ± 0.8 8.0 ± 1.1 95.7 ± 4.3* nd
Norepinephrine 29.5 ± 1.1 35.2 ± 1.7 24.1 ± 1.0 159 ± 3.2* nd
Nicotinamide 39.0 ± 10.9 32.1 ± 2.2 27.8 ± 5.1 130 ± 9.5* nd
Urate 4.5 ± 1.5 7.4 ± 4.3 4.5 ± 0.13 4.6 ± 2.1 nd
Ascorbate 9.0 ± 2.1 10.1 ± 1.0 5.5 ± 0.3 6.5 ± 0.7 nd

nd not done

*

Statistically significant from pFLAG vector, P < 0.05