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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Nat Chem Biol. 2011 Apr 17;7(6):351–358. doi: 10.1038/nchembio.558

Fig. 4. The STIM1 K-domain is essential for heat-induced STIM1 clustering.

Fig. 4

(a) CPA-induced store depletion and SOCE (left panel) or temperature responses (right panel) of HeLa cells transfected with the indicated constructs. (b–c) Confocal analysis of HeLa cells co-transfected with Orai1 and the indicated constructs at 25°C (upper panels) or after heating to the indicated temperatures (lower panels). GFP intensity plots represent localization of each construct across the cell as indicated by the white line.