Table 2. Femorotibial subregions.

Change in cartilage thickness (ThCtAB) over 12 months in knees without baseline JSN (no-JSN, n=308) and with baseline JSN (JSN, n=299).

	no-JSN			JSN			Between-Group
	MC [µm]	SD [µm]	MC [%]	MC [µm]	SD [µm]	MC [%]	DIFF [µm]	CI [µm]	p-value	SL
cMT	−8	91	−0.3	−24	103	−1.0	16	0 / 31	.042	.003
eMT	−6	80	−0.4	−21	88	−1.6	15	1 / 28	.009	.003
iMT	−4	65	−0.2	−8	70	−0.4	4	−7 / 15	.331	.003
aMT	4	64	0.2	3	69	0.2	1	−10 / 11	.775	.003
pMT	1	57	0.1	−8	61	−0.5	9	0 / 18	.022	.003
ccMF	−23	122	−1.0	−49	150	−2.5	26	4 / 48	.030	.003
ecMF	−4	84	−0.2	−22	105	−1.7	19	4 / 34	.008	.003
icMF	−7	69	−0.4	−22	86	−1.2	15	2 / 27	.031	.003
cLT	−21	98	−0.7	−49	139	−1.8	28	9 / 47	.016	.003
eLT	−6	67	−0.3	−16	81	−1.1	11	−1 / 23	.270	.003
iLT	−16	70	−0.8	−29	100	−1.7	13	−1 / 27	.220	.003
aLT	0	61	0.0	−5	75	−0.3	5	−5 / 16	.235	.003
pLT	−11	91	−0.6	−11	105	−0.6	0	−16 / 16	.715	.003
ccLF	2	85	0.1	−14	127	−0.6	15	−2 / 33	.123	.003
ecLF	4	71	0.3	−6	90	−0.4	10	−3 / 23	.279	.003
icLF	0	69	0.0	−4	85	−0.3	5	−8 / 17	.447	.003

MC = mean change in µm or %, SD = standard deviation, DIFF = mean difference between changes, CI = 95% confidence intervals of differences between changes (lower / upper limit), SL = Significance level after Bonferroni-Dunn correction: The significance (p value) of the differences between changes in JSN and no-JSN knees was computed using non-parametric Wilcoxon rank-sum tests and is reported in the table without adjustment for multiple comparisons. None of the femorotibial subregions showed significant differences after Bonferroni-Dunn correction (p<0.0031). (c|e|i|a|p = central|external|internal|anterior|posterior subregion of the medial tibia (MT) or lateral (LT) tibia. c|e|i = central|external|internal subregion of the central part of the medial weight-bearing femur (cMF) or lateral weight-bearing femur (cLF).