Table 3. Femorotibial orders (ordered value approach).
Change in cartilage thickness (ThCtAB) over 12 months in knees without baseline JSN (no-JSN, n=308) and with baseline JSN (JSN, n=299).
| no-JSN | JSN | Between-Group | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MC [µm] |
SD [µm] |
MC [%] |
MC [µm] |
SD [µm] |
MC [%] |
DIFF [µm] |
CI [µm] |
p-value | SL | |
| Medial approach: | ||||||||||
| mOV 1 | −98 | 101 | −5.0 | −125 | 125 | −7.0 | 28 | 9 / 46 | 3.3E−4* | 6.3E−3 |
| mOV 2 | −62 | 80 | −3.6 | −78 | 85 | −4.8 | 16 | 2 / 29 | .004* | 6.3E−3 |
| mOV 3 | −33 | 50 | −1.9 | −50 | 70 | −3.0 | 17 | 7 / 27 | .001* | 6.3E−3 |
| mOV 4 | −13 | 45 | −0.7 | −26 | 60 | −1.6 | 12 | 4 / 21 | .009 | 6.3E−3 |
| mOV 5 | 6 | 42 | 0.4 | −4 | 52 | −0.2 | 10 | 3 / 18 | .011 | 6.3E−3 |
| mOV 6 | 26 | 42 | 1.5 | 17 | 51 | 1.0 | 9 | 1 / 16 | .016 | 6.3E−3 |
| mOV 7 | 48 | 46 | 2.7 | 41 | 59 | 2.4 | 7 | −1 / 16 | .032 | 6.3E−3 |
| mOV 8 | 81 | 52 | 4.5 | 76 | 65 | 4.5 | 5 | −4 / 15 | .198 | 6.3E−3 |
| Extended approach: | ||||||||||
| eOV 1 | −136 | 104 | −6.5 | −181 | 144 | −9.4 | 45 | 25 / 65 | 5.4E−7* | 3.1E−3 |
| eOV 2 | −97 | 80 | −5.3 | −126 | 95 | −7.3 | 29 | 15 / 43 | 9.6E−7* | 3.1E−3 |
| eOV 3 | −69 | 50 | −3.7 | −95 | 78 | −5.4 | 27 | 16 / 37 | 5.7E−7* | 3.1E−3 |
| eOV 4 | −53 | 43 | −2.8 | −73 | 61 | −4.2 | 20 | 12 / 29 | 1.5E−5* | 3.1E−3 |
| eOV 5 | −40 | 40 | −2.1 | −57 | 55 | −3.2 | 17 | 9 / 25 | 9.5E−5* | 3.1E−3 |
| eOV 6 | −29 | 39 | −1.5 | −43 | 50 | −2.5 | 15 | 8 / 22 | 2.2E−4* | 3.1E−3 |
| eOV 7 | −19 | 37 | −1.0 | −31 | 45 | −1.8 | 12 | 6 / 19 | .001 | 3.1E−3 |
| eOV 8 | −9 | 35 | −0.5 | −19 | 43 | −1.1 | 10 | 4 / 16 | .006 | 3.1E−3 |
| eOV 9 | 1 | 34 | 0.0 | −7 | 42 | −0.4 | 8 | 2 / 14 | .032 | 3.1E−3 |
| eOV 10 | 10 | 32 | 0.5 | 4 | 43 | 0.2 | 6 | 0 / 12 | .099 | 3.1E−3 |
| eOV 11 | 21 | 32 | 1.2 | 16 | 43 | 0.9 | 4 | −2 / 10 | .340 | 3.1E−3 |
| eOV 12 | 31 | 31 | 1.7 | 28 | 43 | 1.7 | 3 | −3 / 9 | .786 | 3.1E−3 |
| eOV 13 | 44 | 33 | 2.4 | 42 | 44 | 2.5 | 2 | −4 / 8 | .721 | 3.1E−3 |
| eOV 14 | 59 | 37 | 3.2 | 61 | 48 | 3.5 | −1 | −8 / 5 | .369 | 3.1E−3 |
| eOV 15 | 79 | 43 | 4.2 | 81 | 55 | 4.7 | −1 | −9 / 6 | .557 | 3.1E−3 |
| eOV 16 | 112 | 55 | 5.8 | 116 | 71 | 6.5 | −4 | −14 / 6 | .505 | 3.1E−3 |
MC = mean change in µm or %, SD = standard deviation, DIFF = mean difference between changes, CI = 95% confidence intervals of differences between changes (lower / upper limit), SL = Significance level after Bonferroni-Dunn correction: The significance (p value) of the differences between changes in JSN and no-JSN knees was computed using non-parametric Wilcoxon rank-sum tests and is reported in the table without adjustment for multiple comparisons. Medial and extended ordered values showing significant differences after Bonferroni-Dunn correction (p<0.0063 for medial, p<0.0031 for extended ordered values) are marked with *.
Ordered values were computed from subregional changes in 8 (medial approach)/ 16 (extended approach) subregions in the medial (medial approach) / medial and lateral (extended approach) femorotibial joint. Ordered value (OV) 1 = subregion showing the most negative change (decrease in ThCtAB) in each subject, OV 2 = subregion showing the second most negative change, ….OV 8 (medial approach) / 16 (extended approach) = subregion showing the smallest negative or the greatest positive change (increase in ThCtAB).