Table 5.
Percentage of p-values less than 0.05 computed using the bootstrapping method between knees without and with joint space narrowing (JSN) and computed using a randomization of knees with JSN.
| Bootstrap (no-JSN vs. JSN knees) | Randomization (JSN knees) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| aSL | % (p<SL) | % (p<aSL) | Median | SD | % (p<SL) | % (p<aSL) | Median | SD | |
| Regional approach: | |||||||||
| MFTC | 0.0250 | 84.7 | 76.9 | 2.6E-03 | 0.09 | 4.9 | 2.6 | 0.50 | 0.29 |
| LFTC | 0.0250 | 34.8 | 25.4 | 0.11 | 0.27 | 4.9 | 2.4 | 0.50 | 0.29 |
| MT | 0.0125 | 60.4 | 39.4 | 0.03 | 0.19 | 4.8 | 1.2 | 0.50 | 0.29 |
| cMF | 0.0125 | 77.8 | 58.6 | 0.01 | 0.12 | 5.0 | 1.2 | 0.50 | 0.29 |
| LT | 0.0125 | 29.8 | 14.5 | 0.15 | 0.28 | 5.1 | 1.3 | 0.49 | 0.29 |
| cLF | 0.0125 | 22.9 | 10.6 | 0.22 | 0.29 | 4.7 | 1.1 | 0.50 | 0.29 |
| cMT | 0.0031 | 50.0 | 16.4 | 0.05 | 0.22 | 5.0 | 0.3 | 0.50 | 0.29 |
| eMT | 0.0031 | 75.0 | 37.6 | 0.01 | 0.13 | 4.8 | 0.3 | 0.50 | 0.29 |
| iMT | 0.0031 | 16.7 | 2.5 | 0.31 | 0.30 | 4.6 | 0.2 | 0.50 | 0.29 |
| aMT | 0.0031 | 5.8 | 0.4 | 0.49 | 0.29 | 4.9 | 0.3 | 0.50 | 0.29 |
| pMT | 0.0031 | 60.1 | 22.9 | 0.03 | 0.18 | 5.0 | 0.3 | 0.50 | 0.29 |
| ccMF | 0.0031 | 60.7 | 23.9 | 0.03 | 0.19 | 5.1 | 0.4 | 0.50 | 0.29 |
| ecMF | 0.0031 | 76.7 | 39.8 | 0.01 | 0.12 | 5.3 | 0.3 | 0.49 | 0.29 |
| icMF | 0.0031 | 59.0 | 22.3 | 0.03 | 0.20 | 4.9 | 0.2 | 0.51 | 0.29 |
| cLT | 0.0031 | 65.7 | 28.0 | 0.02 | 0.17 | 4.9 | 0.4 | 0.50 | 0.29 |
| eLT | 0.0031 | 17.7 | 2.7 | 0.28 | 0.30 | 4.9 | 0.4 | 0.50 | 0.29 |
| iLT | 0.0031 | 19.7 | 3.1 | 0.26 | 0.30 | 4.4 | 0.3 | 0.50 | 0.29 |
| aLT | 0.0031 | 23.3 | 4.3 | 0.21 | 0.29 | 5.5 | 0.4 | 0.50 | 0.29 |
| pLT | 0.0031 | 7.6 | 0.8 | 0.46 | 0.30 | 5.0 | 0.3 | 0.50 | 0.29 |
| ccLF | 0.0031 | 32.3 | 7.5 | 0.13 | 0.27 | 4.9 | 0.2 | 0.50 | 0.29 |
| ecLF | 0.0031 | 18.9 | 3.2 | 0.27 | 0.30 | 5.0 | 0.4 | 0.50 | 0.29 |
| icLF | 0.0031 | 10.7 | 1.2 | 0.40 | 0.30 | 4.6 | 0.3 | 0.51 | 0.29 |
| Medial ordered values: | |||||||||
| mOV 1 | 0.0063 | 93.7 | 77.6 | 4.5E-04 | 0.05 | 5.1 | 0.6 | 0.50 | 0.29 |
| mOV 2 | 0.0063 | 79.9 | 52.6 | 4.9E-03 | 0.11 | 5.1 | 0.6 | 0.50 | 0.29 |
| mOV 3 | 0.0063 | 89.8 | 69.8 | 1.2E-03 | 0.07 | 5.3 | 0.6 | 0.50 | 0.29 |
| mOV 4 | 0.0063 | 73.7 | 44.4 | 0.01 | 0.14 | 4.9 | 0.6 | 0.50 | 0.29 |
| mOV 5 | 0.0063 | 73.1 | 43.9 | 0.01 | 0.14 | 4.9 | 0.7 | 0.50 | 0.29 |
| mOV 6 | 0.0063 | 70.7 | 40.6 | 0.01 | 0.15 | 4.7 | 0.6 | 0.50 | 0.29 |
| mOV 7 | 0.0063 | 61.9 | 31.9 | 0.02 | 0.18 | 4.8 | 0.6 | 0.49 | 0.29 |
| mOV 8 | 0.0063 | 30.4 | 10.0 | 0.15 | 0.28 | 5.0 | 0.7 | 0.50 | 0.29 |
| Extended ordered values: | |||||||||
| eOV 1 | 0.0031 | 99.8 | 96.7 | 1.9E-06 | 0.01 | 5.0 | 0.3 | 0.49 | 0.29 |
| eOV 2 | 0.0031 | 99.7 | 96.2 | 2.2E-06 | 0.01 | 4.9 | 0.2 | 0.49 | 0.29 |
| eOV 3 | 0.0031 | 99.9 | 97.4 | 1.0E-06 | 0.00 | 5.1 | 0.3 | 0.49 | 0.29 |
| eOV 4 | 0.0031 | 98.9 | 90.0 | 2.1E-05 | 0.02 | 5.0 | 0.3 | 0.49 | 0.29 |
| eOV 5 | 0.0031 | 96.7 | 80.1 | 1.4E-04 | 0.03 | 5.0 | 0.2 | 0.50 | 0.29 |
| eOV 6 | 0.0031 | 94.8 | 74.0 | 3.1E-04 | 0.05 | 5.2 | 0.3 | 0.49 | 0.29 |
| eOV 7 | 0.0031 | 90.2 | 62.2 | 1.1E-03 | 0.07 | 5.1 | 0.3 | 0.50 | 0.29 |
| eOV 8 | 0.0031 | 75.3 | 38.5 | 0.01 | 0.13 | 5.2 | 0.4 | 0.50 | 0.29 |
| eOV 9 | 0.0031 | 54.9 | 19.3 | 0.03 | 0.20 | 4.9 | 0.3 | 0.49 | 0.29 |
| eOV 10 | 0.0031 | 36.5 | 8.8 | 0.10 | 0.27 | 5.1 | 0.3 | 0.50 | 0.29 |
| eOV 11 | 0.0031 | 17.0 | 2.2 | 0.29 | 0.30 | 5.0 | 0.3 | 0.50 | 0.29 |
| eOV 12 | 0.0031 | 6.1 | 0.4 | 0.47 | 0.29 | 5.0 | 0.3 | 0.50 | 0.29 |
| eOV 13 | 0.0031 | 7.8 | 0.7 | 0.45 | 0.30 | 4.7 | 0.3 | 0.50 | 0.29 |
| eOV 14 | 0.0031 | 10.8 | 1.4 | 0.39 | 0.30 | 5.0 | 0.3 | 0.51 | 0.29 |
| eOV 15 | 0.0031 | 6.8 | 0.6 | 0.46 | 0.29 | 4.9 | 0.3 | 0.50 | 0.29 |
| eOV 16 | 0.0031 | 7.6 | 0.7 | 0.45 | 0.30 | 4.8 | 0.3 | 0.50 | 0.29 |
SL = Significance level (0.0). aSL = Significance level (0.05) adjusted for multiple comparisons. % (p<SL) = Percentage of p-values less than the significance level. %(p<aSL) = Percentage of p-values less than the adjusted significance level (aSL). Median = Median p-value obtained from the p-values computed after each of the 10,000 bootstrapping runs (no-JSN vs JSN knees) and after each of the 10,000 randomization runs (JSN knees vs. JSN knees). SD = standard deviation of the p-values;. All p-values were computed using non- parametric Wilcoxon rank-sum tests. (c|e|i|a|p = central|external|internal|anterior|posterior subregion of the medial tibia (MT) or lateral (LT) tibia. c|e|i = central|external|internal subregion of the central part of the medial weight-bearing femur (cMF) or lateral weightbearing femur (cLF). Ordered values were computed from subregional changes in 8 (medial approach: mOV 1–8)/ 16 (extended approach: eOV 1–16) subregions in the medial (medial approach) / medial and lateral (extended approach) femorotibial joint.