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Glioblastoma recurrence. a,b Pre-treatment brain MRI. c,d Post-instillation CT showing magnetic nanoparticle deposits as hyperdense areas. Isothermal lines indicate calculated treatment temperatures between 40°C (blue) and 50°C (red). The brown line represents the tumor area. e,f 3-D reconstruction of fused MRI and CT showing the tumor (brown), magnetic fluid (blue) and thermometry catheter (green)
