Table 3.
Average Lifetime Risk | 0 Kidney Risk Variants | 1 Kidney Risk Variant | 2 Kidney Risk Variants | |
---|---|---|---|---|
HIV-CG (without antiretroviral therapy) | 10% | 0% (0, 6) | 5% (3, 8) 1:20 | 20% (15, 25) 1:5 |
FSGS | 0.8% | 0.2% (0.1, 0.4) 1:500 | 0.4% (0.3, 0.5) 1:250 | 1.6% (1.4, 1.8) 1:62 |
Hypertension-attributed ESKD | 2.25% | 1.4% (1.1, 1.7) 1:71 | 1.9% (1.7, 2.1) 1:53 | 3.1% (2.8, 33) 01:32 |
NOTE. Lifetime risks were estimated, as described in the text, for 0, 1, and 2 copies of the MYH9 E-1 kidney risk variant. Numbers in parentheses are 95% confidence intervals.