Fig. 1.
a Effect of chronic 5-HT infusion on mean arterial pressure (MAP) in male SERT WT and SERT KO rats. b Effect of chronic 5-HT infusion on mean arterial pressure (MAP) in female SERT WT and SERT KO rats. Data points indicate 24-h averaged MAP±SEM for the number of animals in parentheses. The vertical line denotes 5-HT or vehicle osmotic pump implant. Time is represented by days on the x-axis. C represents control recordings. S represents 5-HT infusion. Single asterisk reperesents statistically significant (p<0.05) difference compared with male SERT KO rat. Single dagger sign represents statistically significant (p<0.05) difference compared to control (C2) in male SERT WT rat. Single number sign represents statistically significant (p<0.05) difference compared to control (C2) in female SERT KO rat (C2)