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Enzymatic inhibition (IC50, μM)
| PGI | GAPDH | PyK | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Compound | T. brucei | Rabbit muscle | T. brucei | Rabbit muscle | L. mexicana | Rabbit muscle | |
| 1 | 30 ± 10 | n.i. | 30 ± 10 | n.i. | 30 ± 5 | 80 ± 10 | |
| 2 | 45 ± 10 | n.i. | n.i. | n.i. | n.i. | n.i. | |
n.i. … no inhibition observed at a concentration of 50 μM.
