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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Clin Lipidol. 2010 Dec 1;5(6):867–897. doi: 10.2217/clp.10.67

Table 1.

Other selected Sec14-like proteins.

Gene Protein Description Ref.
BNIP-2 BNIP-2 Proapoptotic and promotes Cdc42-mediated cell elongation through its Sec14-like domain [85,194196]
BNIPL BNIPL/BNIPL2 Proapoptotic, increases cell migration and may play a role in metastasis [85,197,198]
BMCC1/BNIP-XL BMCC1/BNIP-XL Proapoptotic protein highly expressed in the human nervous system. Interacts with RhoA via Sec14 domain and is a favorable signature in neuroblastomas [85,199202]
BPGAP1 BPGAP1 Promotes pseudopodia formation, Erk signaling. Elevated levels associated with colorectal cancer and invasive cervical cancer [203207]
CRALBPL/RLBP1L1 Clavesin1 Regulates late endosome/lysosome morphology in neurons and is upregulated in hepatocellular carcinoma [208210]
Clavesin2 Regulates late endosome/lysosome morphology in neurons [210]
Sec14L1 SEC14L1 Regulates cholinergic transporters and synaptic vesicle formation [139,211]
Sec14L5 SEC14L5 Unknown [139]
Sec14L2 SEC14L2/TAP1/SPF Plays a role in cholesterol synthesis during fasting. In humans, a potential link to breast carcinogenesis and prostate cancer [139,212216]
Sec14L3 SEC14L3/TAP2/p45 Potential link with drug-induced lung adenocarcinoma in mice [139,217,218]
Sec14L4 SEC14L4/TAP3 Unknown [139]
SESTD1 Solo/HIPLP Elevated levels in the thalamus and brain with potential functions in cone guidance and smooth muscle contraction [219,220,210]
MOSPD2 MSPD2 Unknown function in humans but is localized with zebrafish maternal expression in eggs [221]