BNIP-2 |
BNIP-2 |
Proapoptotic and promotes Cdc42-mediated cell elongation through its Sec14-like domain |
[85,194–196] |
BNIPL |
BNIPL/BNIPL2 |
Proapoptotic, increases cell migration and may play a role in metastasis |
[85,197,198] |
BMCC1/BNIP-XL |
BMCC1/BNIP-XL |
Proapoptotic protein highly expressed in the human nervous system. Interacts with RhoA via Sec14 domain and is a favorable signature in neuroblastomas |
[85,199–202] |
BPGAP1 |
BPGAP1 |
Promotes pseudopodia formation, Erk signaling. Elevated levels associated with colorectal cancer and invasive cervical cancer |
[203–207] |
CRALBPL/RLBP1L1 |
Clavesin1 |
Regulates late endosome/lysosome morphology in neurons and is upregulated in hepatocellular carcinoma |
[208–210] |
|
Clavesin2 |
Regulates late endosome/lysosome morphology in neurons |
[210] |
Sec14L1 |
SEC14L1 |
Regulates cholinergic transporters and synaptic vesicle formation |
[139,211] |
Sec14L5 |
SEC14L5 |
Unknown |
[139] |
Sec14L2 |
SEC14L2/TAP1/SPF |
Plays a role in cholesterol synthesis during fasting. In humans, a potential link to breast carcinogenesis and prostate cancer |
[139,212–216] |
Sec14L3 |
SEC14L3/TAP2/p45 |
Potential link with drug-induced lung adenocarcinoma in mice |
[139,217,218] |
Sec14L4 |
SEC14L4/TAP3 |
Unknown |
[139] |
SESTD1 |
Solo/HIPLP |
Elevated levels in the thalamus and brain with potential functions in cone guidance and smooth muscle contraction |
[219,220,210] |
MOSPD2 |
MSPD2 |
Unknown function in humans but is localized with zebrafish maternal expression in eggs |
[221] |