Table 1.
Other selected Sec14-like proteins.
| Gene | Protein | Description | Ref. |
|---|---|---|---|
| BNIP-2 | BNIP-2 | Proapoptotic and promotes Cdc42-mediated cell elongation through its Sec14-like domain | [85,194–196] |
| BNIPL | BNIPL/BNIPL2 | Proapoptotic, increases cell migration and may play a role in metastasis | [85,197,198] |
| BMCC1/BNIP-XL | BMCC1/BNIP-XL | Proapoptotic protein highly expressed in the human nervous system. Interacts with RhoA via Sec14 domain and is a favorable signature in neuroblastomas | [85,199–202] |
| BPGAP1 | BPGAP1 | Promotes pseudopodia formation, Erk signaling. Elevated levels associated with colorectal cancer and invasive cervical cancer | [203–207] |
| CRALBPL/RLBP1L1 | Clavesin1 | Regulates late endosome/lysosome morphology in neurons and is upregulated in hepatocellular carcinoma | [208–210] |
| Clavesin2 | Regulates late endosome/lysosome morphology in neurons | [210] | |
| Sec14L1 | SEC14L1 | Regulates cholinergic transporters and synaptic vesicle formation | [139,211] |
| Sec14L5 | SEC14L5 | Unknown | [139] |
| Sec14L2 | SEC14L2/TAP1/SPF | Plays a role in cholesterol synthesis during fasting. In humans, a potential link to breast carcinogenesis and prostate cancer | [139,212–216] |
| Sec14L3 | SEC14L3/TAP2/p45 | Potential link with drug-induced lung adenocarcinoma in mice | [139,217,218] |
| Sec14L4 | SEC14L4/TAP3 | Unknown | [139] |
| SESTD1 | Solo/HIPLP | Elevated levels in the thalamus and brain with potential functions in cone guidance and smooth muscle contraction | [219,220,210] |
| MOSPD2 | MSPD2 | Unknown function in humans but is localized with zebrafish maternal expression in eggs | [221] |