Table 3.
Multivariate analyses of factors associated with early (<24 h) packed red blood cell (PRBC) transfusions, late (>24 h) PRBC transfusions, open pelvic surgery, and mortality
| Parameter | Predictors of early (<24 h) PRBC transfusion | Predictors of late (beyond 24 h) PRBC transfusion | Factors associated with open pelvic surgery | Predictors of mortality | ||||
|---|---|---|---|---|---|---|---|---|
| Class: Sub-grouping | Univariate, P-value | Multivariate, P-value (Wald statistic) | Univariate, P-value | Multivariate, P-value, (Wald statistic) | Univariate, P-value | Multivariate, P-value (Wald statistic) | Univariate, P-value | Multivariate, P-value (Wald statistic) |
| Demographic: Age | 0.204 | 0.011 | <0.001 | 0.004 (8.12) | 0.062 | |||
| Demographic: Gender | 0.064 | 0.017 | 0.015 (5.95) | 0.005 | ||||
| Coagulation: INR | 0.014 | 0.001 | ||||||
| Coagulation: PT | ||||||||
| Coagulation: PTT | 0.022 | 0.003 | ||||||
| Hematologic: Any blood products given–Initial 24 h | <0.001 | 0.484 | 0.008 | |||||
| Hematologic: Corrected hemoglobin drop–Initial 24 h | <0.001 | 0.106 | 0.109 | |||||
| Hematologic: Initial hemoglobin | <0.001 | 0.024 (5.12) | 0.164 | 0.008 | ||||
| Hematologic: Fresh frozen plasma transfusion >24 h | 0.010 | 0.003 | ||||||
| Hematologic: PRBC transfusion–Initial 24 h | <0.001 | <0.001 | ||||||
| Hematologic: PRBC transfusion >24 h | <0.001 | <0.001 (12.8) | ||||||
| Pharmacologic: Any antiplatelet agent use | 0.307 | 0.060 | 0.008 (7.096) | 0.085 | 0.656 | |||
| Pharmacologic: Acetylsalicylic acid use | 0.049 | 0.020 (5.42) | 0.915 | |||||
| Pharmacologic: Clopidogrel use | 0.610 | 0.091 | ||||||
| Pharmacologic: High-dose/scheduled NSAID | 0.238 | |||||||
| Metric: Injury severity score | <0.001 | 0.025 (5.03) | 0.027 | 0.536 | <0.001 | 0.014 (4.28) | ||
| Metric: Number of associated non-PFx injuries | <0.001 | <0.001 | 0.154 | 0.005 | ||||
| Metric: Number of complications | <0.001 | 0.003 (10.5) | 0.133 | <0.001 | 0.015 (6.68) | |||
| Metric: Pelvic fracture severity score | 0.001 | 0.008 (7.003) | <0.001 | 0.047 (3.94) | 0.051 | 0.010 (6.70) | 0.035 | 0.034 (4.51) |
| Procedural: Need for IR intervention | 0.095 | 0.238 | 0.467 | 0.367 | ||||
| Procedural: Need for open pelvic surgery | <0.001 | 0.002 (9.40) | 0.029 | 0.011 (6.82) | ||||
| Radiographic: Hematoma/contrast extravasation on CT | 0.029 | 0.002 | 0.156 | 0.009 (6.89) | 0.010 | 0.027 (4.92) | ||