Table 1.
Patient details. * Prophylaxis consisted of itraconazole and granulocyte colony stimulating factor (GCSF).
| Case | Age/Sex | Disease | Prophylaxis* | Sites | Fungus | Outcome | Radiological features |
| 1 | 4/F | AML | No | Sinuses | Mucor species | Resolved | CT – Sinus disease with destruction of medial wall of right antrum . |
| 2 | 1/F | ALL | No | Lungs kidneys | Aspergillus | Resolved | CXR – Consolidation of left lower lobe. CT – Cavitation in left lower lobe. Large kidneys with many low attenuation areas. |
| 3 | 4/M | AML | No | Lungs | Presumed resolved after Amphotericin | Succumbed to klebsiella sepsis | CXR – Lung nodules which subsequently cavitated |
| 4 | 6 months/M | AML | No | Lungs, liver, oesophagus | Candida from oesophagus | Died | No abnormal radiological features |
| 5 | 6/F | ALL | No | Liver, spleen, kidneys, skin | Unidentified fungal elements from skin | Died | CT – Multiple low attentuation areas in liver, spleen and kidneys |
| 6 | 1/F | AML | Yes | Lungs | None isolated but clinical course suggested fungal infection | Died | CXR – Bilateral lung consolidation |
| 7 | 7/M | ALL | Yes | Blood, liver | Candida tropicalis | Died | No abnormal radiological features |
| 8 | 3/M | ALL | No | Liver, spleen, | None isolated | Resolved | CT – Hypodense lesions in liver and spleen |
| 9 | 12/M | AML | Yes | Blood, sinuses, lungs | Fusarium oxysporon from blood | Died | CT – Sinus disease in antra. Small lung nodules and consolidation which cavitated. |
| 10 | 2/F | ALL | Yes | Blood | Candida pelliculosa | Cured | No abnormal radiological features |
| 11 | 1/F | Medulloblastoma | No | Lungs | Candida albicans. Trichosporon species | Died | CXR – Bilateral upper lobe consolidation |
| 12 | 5/F | Neuroblastoma | Yes | Lungs | Presumed | Cured | CXR – Bilateral lung consolidation |
| 13 | 3/M | ALL | Yes | Sinuses | None isolated but presumed | Remission | CT – Mucosal thickening both antra. With destruction of lateral wall right maxillary antrum |
| 14 | 7/M | ALL | Yes | Sinuses | None isolated | Remission | CT – Pansinusitis. Hepatosplenomegaly. Cerebral venous thrombosis. Small enhancing cerebral lesions |
| 15 | 9/F | AML | Yes | Lungs | Aspergillus candida tropicalis | Delayed chemotherapy | CXR and CT – Lung nodules which cavitated. Mycotic pulmonary artery aneurysm |
| 16 | 3/M | Sacrococcygeal tumour | No | Blood | Paecilomyces | Died | CT – Nodules increasing on anti fungal treatment |
| 17 | 3/M | ALL | Yes | Lungs | None isolated | Died | CXR – Consolidation right lower and left upper lobes |
| 18 | 11/F | AML | Yes | Lungs | None isolated | Died | CXR – Consolidation right lung |
| 19 | 5 months/M | Neuroblastoma | No | Blood | Candida | Delayed chemotherapy | CT – Adrenal tumour. Hypodense liver lesions thought to be metastases |