Figure 1.

BCG vaccination with 2–8 × 10⁶ CFU BCG Danish strain 1331 reduced the severity and progression of experimental bovine TB in badgers. Badgers were vaccinated and then challenged 17 weeks later with endobronchial M. bovis. Disease severity was assessed post-mortem 12 weeks after challenge. Only lesions subsequently confirmed to be caused by M. bovis by bacterial culture or histology were used to calculate the lesion score. The data for individual animals from two separate experiments (VES1 and VES2) are shown together with the group median. Filled circles, non-vaccinated; filled squares, BCG. The score for one animal (D313) is indicated where vaccination failed to protect.