Table 3.

Latency and peak of insular cortex and amygdala activity after immune challenge. Data are expressed as minutes; latency, first significant change from baseline; peak, maximal deviation from baseline; (+) or (−) signs indicate the direction of change in comparison to baseline; n.s., not significant.

	naive (day 1)				desensitization (day 5)
	insular cortex		amygdala		insular cortex		amygdala
	latency	peak	latency	peak	latency	peak	latency	peak
LPS	140 (+)	185 (+)	65 (−)	n.s.	65 (+)	140 (+)	65 (+)	110 (+)
SEB	50 (+)	140 (+)	65 (+)	140 (+)	n.s.	n.s.	n.s.	n.s.