Table 3.
Predictor | Adjustment variablesa | Cognitive measurement |
||||
---|---|---|---|---|---|---|
ADAS-Cog | MMSE | Auditory–Verbal Learning Test | Boston Naming | Trails B | ||
Predictor variable | ||||||
Amyloid-β1-42 | −0.27** | 0.19** | 0.21** | 0.00 | −0.09 | |
STAND | 0.51** | −0.35** | −0.27** | −0.29** | 0.33** | |
t-tau | 0.22** | −0.19** | −0.23** | −0.12* | 0.14* | |
WMH | 0.11 | −0.06 | −0.05 | −0.15* | 0.23** | |
AMNART | 0.14* | −0.21** | −0.03 | −0.37** | 0.22** | |
AMNART adjusted for biomarkers | ||||||
AMNART | Amyloid-β1-42 | 0.16** | −0.22** | −0.04 | −0.37** | 0.23** |
AMNART | STAND | 0.14* | −0.20** | −0.02 | −0.37** | 0.22** |
AMNART | t-tau | 0.14* | −0.20** | −0.02 | −0.37** | 0.22** |
AMNART | WMH | 0.15* | −0.21** | −0.04 | −0.37** | 0.22** |
AMNART | Amyloid-β1-42, t-tau, STAND and WMH | 0.16** | −0.21** | −0.02 | −0.37** | 0.21** |
Biomarkers adjusted for AMNART | ||||||
Amyloid-β1-42 | −0.28** | 0.20** | 0.21** | 0.02 | −0.10 | |
STAND | 0.51** | −0.35** | −0.26** | −0.29** | 0.33** | |
t-tau | 0.22** | −0.17** | −0.22** | −0.12 | 0.14* | |
WMH | 0.10 | −0.04 | −0.05 | −0.13* | 0.21** |
a Age and gender are included.
STAND = Structural Abnormality Index; WMH = white matter hyperintensity.
*P value between 0.01 and 0.05.
**P value < 0.01.