Table 3.
The malaria-attributable fractions for seizures, the predicted and the observed decrease in the incidence of seizures and the proportion of the observed decrease that occurred in malaria-associated seizures
| Type of seizures | Adjusted malaria- attributable fractions for seizures (95% CI) | Predicted decline in seizures using malaria-attributable fractions/100 000/year | Observed decrease in seizures/100 000/year (percentage decrease) | Proportion of the observed decrease that occurred in MAS |
|---|---|---|---|---|
| All acute symptomatic seizures | 92.9% (90.4–95.1%) | 794 | 809 (69.2%) | 753/100 000/year (93.1%) |
| Convulsive status epilepticus | 92.9% (89.4–95.5%) | 129 | 111 (57.2%) | 111/100 000/year (100%) |
| Repetitive seizures | 93.6% (90.9–95.9%) | 404 | 440 (73.7%) | 382/100 000/year (86.8%) |
| Focal seizures | 91.8% (85.6–95.4%) | 125 | 153 (80.5%) | 129/100 000/year (84.3%) |
The predicted decline in the incidence of seizures was the incidence of MAS in 2002 (the beginning of the study) multiplied by the malaria-attributable fractions for seizures. Annual incidences of seizures are provided in Table 2. The observed decrease in the incidence of seizures was the difference in the incidence between 2002 and 2008 (the end of study). Percentage decrease was the decrease in the incidence expressed as a percentage of the incidence at 2002.