MSCs |
Multipotent and pluripotent. Bone marrow is the major source of MSC |
MSCs are capable of differentiating into bone, cartilage, fat, muscle, marrow stroma, and other tissue types |
ESCs |
Derived from an early stage embryo and can differentiate into derivatives of all three primary germ layers. ESCs are multipotent and pluripotent |
Can differentiate into brain and nervous system cells, insulin producing cells of the pancreas, bone cells, hematopoietic cells, endothelial cells, cardiomyocytes |
ASCs |
Multipotent, oligopotent, or unipotent progenitor cells. Derived from a more mature tissue, such as the umbilical cord, bone marrow, or skin |
To treat leukemia and related bone/blood cancers through bone marrow transplants |
HSCs |
Found in the bone marrow. Multipotent |
All types of blood cells |
iPS |
Derived from epithelial cells. Pluripotent |
The iPS cell lines could be differentiated into heart muscle and neuronal cells, in addition to basic cell types (ectoderm, mesoderm, and endoderm) |
Mammary stem cells |
Isolated from human and mouse tissue |
Growth of mammary glands |
Endothelial stem cells |
Multipotent cells found in the bone marrow |
Can differentiate into endothelial cells, the cells that make up the lining of blood vessels |