Table 1.

Hints towards an innate immunity involvement in primary biliary cirrhosis

	Peculiarity
Monocytes	Increase in absolute number
	Increase in pro-inflammatory cytokines upon infectious challenge
Elevated IgM	B cell response to bacterial stimuli
NKT cells	Increased NKT cells in PBC peripheral blood and liver
	Increased NKT cytotoxic activity
Liver histology	Focal duct obliteration with granuloma formation

PBC: primary biliary cirrhosis models.