Table 2.

Effects of MPTP on burst parameters

		M1	CSN	PTN
Mean spikes per burst	Pre-MPTP	8.4 ± 4	6.9 ± 3.3	9.9 ± 5.1
	Post-MPTP	7.7 ± 3.6*	6.7 ± 3.2	9.5 ± 4
Intraburst firing rate (sp/s)	Pre-MPTP	39.5 ± 31.2	17.4 ± 19.3	48.2 ± 27.2
	Post-MPTP	43.7 ± 68.2	30.9 ± 55.7	41.8 ± 31.8*
Burst duration (ms)	Pre-MPTP	383 ± 709	756 ± 1297	218 ± 139
	Post-MPTP	364 ± 369	540 ± 515	360 ± 330*
Intraburst coefficient of variation	Pre-MPTP	1.12 ± 0.59	1.32 ± 0.39	0.77 ± 0.49
	Post-MPTP	1.1 ± 0.56	1.19 ± 0.59	0.74 ± 0.4
Neurons with burst-associated movements	Pre-MPTP	52/297 (17%)	4/40 (10%)	11/54 (20%)
	Post-MPTP	20/141 (14%)	2/16 (12%)	5/30 (16%)

Note: Mean values ± SD before and after MPTP treatment are calculated for all M1 cells (left), for CSNs (middle), and for PTNs (right).

*P < 0.05 (Mann–Whitney U-test).