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. Author manuscript; available in PMC: 2012 May 19.
Published in final edited form as: J Phys Chem B. 2011 Apr 27;115(19):6202–6212. doi: 10.1021/jp111112s

Fig. 1. The genetic toggle switch.

Fig. 1

DNA plasmid is shown with promoters pA and pB of genes gA and gB that, when transcribed, produce proteins A and B, respectively. The gene-promoter complex for species A(B) is denoted α(β) in Eq.(1). In this gene circuit, production of A inhibits B or production of B inhibits A. In Eq.(2), this is shown by having A bind to the gene-promoter complex of B, and vice-versa.