Table 1.
Characteristics | EGFR mutant (n = 41) (n [%]) | EGFR wild-type (n = 52) (n [%]) | Total (n = 93) (n [%]) |
---|---|---|---|
Mean age ± SD (yrs) | 60.4 ± 14.1 | 61.3 ± 10.1 | 60.9 ± 12.0 |
Gender | |||
Male | 18 (44) | 13 (25) | 31 (33) |
Female | 23 (56) | 39 (75) | 62 (67) |
Race | |||
Caucasian | 37 (90) | 49 (94) | 86 (93) |
African American | 0 (0) | 0 (0) | 0 (0) |
Asian | 2 (5) | 3 (6) | 5 (5) |
Other | 2 (5) | 0 (0) | 2 (2) |
Histology | |||
Adenocarcinoma | 40 (98) | 47 (90) | 87 (94) |
Squamous | 0 (0) | 1 (2) | 1 (1) |
Large Cell | 1 (2) | 0 (0) | 1 (1) |
Other | 0 (0) | 4 (8) | 4 (4) |
Stage | |||
I | 4 (10) | 5 (10) | 9 (10) |
II | 2 (5) | 2 (4) | 4 (4) |
IIIA | 4 (10) | 5 (10) | 9 (10) |
IIIB | 1 (2) | 3 (6) | 4 (4) |
IV | 30 (73) | 37 (71) | 67 (72) |
Smoking history | |||
Ever | 14 (34) | 39 (75) | 53 (57) |
Never | 27 (66) | 13 (25) | 40 (43) |
Sites of metastatic diseasea | |||
Brain | 20 (67) | 24 (65) | 44 (66) |
Lung | 22 (73) | 15 (41) | 37 (55) |
Liver | 11 (37) | 6 (16) | 17 (25) |
Bone | 18 (60) | 11 (30) | 29 (43) |
Other | 6 (20) | 9 (24) | 15 (22) |
aIn patients with stage IV disease at diagnosis, rows do not necessarily total 100%, as all sites of disease were categorized for each patient.