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. 2010 Aug 2;12(11):1088–1101. doi: 10.1093/neuonc/noq079

Fig. 3.

Fig. 3.

Changes in ability of cell invasion in glioblastoma cells. Treatments (48 hours): control, scrambled siRNA, survivin siRNA, 1 µM 4-HPR, and survivin siRNA + 1 µM 4-HPR. (A) Representative Matrigel invasion assay for U251MG cells. A significant reduction in the number of invaded cells indicated the decrease in invasive potency of the treated cells. (B) Quantitative evaluation of Matrigel invasion assay. The data are mean ± SD of 10 randomly selected microscopic fields from 3 independent wells in each group (*P < .001 compared with the control mean values and #P < .001 compared with the survivin siRNA or 4-HPR mean values).