Figure 6.

The relationship between the DMN and memory search-related activity. a, Whole-brain, multiple-comparison corrected group z-map showing search-related BOLD activations (red to yellow colors) and deactivations (light to dark blue colors) with respect to the baseline in the memory search task. The search parameter was obtained using Search-Corr-HC trials (process GLM) (see Materials and Methods). The borders of the DMN (in white) are superimposed over the activation map to reveal regions of overlap. b, Time courses of BOLD activity, aligned to the onset of the cue sentence (frame-by-frame, between-trial GLM), extracted from five regions showing significant positive and negative memory search-related responses that were located inside the DMN (defined by black borders on the flat map). Time courses were grouped according to the retrieval time interval and refer to catch trials (gray), and early (1–4 s; green), middle (4–8 s; orange), and late (8–12 s; black) correct trials. The horizontal line under the third graph illustrates the temporal duration of the corresponding retrieval intervals.