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. 2010 May 18;11:259. doi: 10.1186/1471-2105-11-259

Table 3.

Cost comparison of Amazon's cloud computing instance types.

Instance Type # Instances Time * (hours) Cost ($)
Standard Small (single core) 50 1088 6256 (0.115 per hour per instance)

Standard Large (dual core) 50 544 12512 (0.46 per hour per instance)

Standard Extra Large (4-cores) 50 272 12512 (0.92 per hour per instance)

High-CPU Medium (dual core) 50 544 6256 (0.23 per hour per instance)

High-CPU Extra Large (8 core) 50 136 6256 (0.92 per hour per instance)

Amazon's Elastic Compute Cloud (EC2) can be accessed via a number of differet instance types. For the purposes of our comparative genomics problem, we elected to utilize the extra-large high-CPU instance. Note that the total cost for a small instance is equal to the total of the extra large, despite the large difference in computing time.