Table 1.
Fisher's exact test for statistically overrepresented pathways among CCA results.
| Pathway | Odds Ratio | Expected Count | Actual Count | Pathway Size | p value |
|---|---|---|---|---|---|
| Selenoamino acid metabolism | 3.240 | 3.694 | 8 | 17 | 0.018 |
| Neuroactive ligand-receptor interaction | 2.265 | 7.388 | 13 | 34 | 0.020 |
| Histidine metabolism | 2.915 | 3.911 | 8 | 18 | 0.026 |
| Arginine and proline metabolism | 2.363 | 6.084 | 11 | 28 | 0.026 |
| Fc epsilon RI signaling pathway | 2.192 | 6.953 | 12 | 32 | 0.030 |
| Pancreatic cancer | 1.961 | 9.343 | 15 | 43 | 0.032 |
| Glycerolipid metabolism | 2.523 | 4.780 | 9 | 22 | 0.033 |
| Steroid biosynthesis | 3.630 | 2.173 | 5 | 10 | 0.045 |
| Heparan sulfate biosynthesis | 3.630 | 2.173 | 5 | 10 | 0.045 |
Expected count represents the expected number of MetS associated genes in each pathway based on the overall number of MetS associated genes in the dataset, total number of genes tested, and size of the pathway.