Table 2.
Results of post mortem pathological study in 3 groups*
| Control (n = 14) | CRS (n = 12)* | CRS+HIPEC (n = 13)§ | P | |
|---|---|---|---|---|
| Ulcerative gastric cancer | 100% | 100% | 100% | NA |
| Pyloric obstruction | 100% | 100% | 100% | NA |
| Gastric perforation | 28.6% | 8.3% | 8.3% | P = 0.246 |
| Greater omentum cake | 100% | removed | removed | NA |
| Liver metastases | 100% | 96.7% | 38.5% | P = 0.000 |
| Pulmonary metastases | 0.0% | 8.3% | 53.8% | P = 0.000 |
| Cancerous diaphragm | 100% | 100% | 53.8% | P = 0.000 |
| Upper abdominal wall cancer | 100% | 100% | 84.6% | P = 0.128 |
| Small intestine & mesentery seeding | 100% | 100% | 61.5% | P = 0.002 |
| Adrenal gland metastases | 100% | 100% | 23.5% | P = 0.000 |
| Kidney capsule invasion | 100% | 75.0% | 30.8% | P = 0.000 |
| Retroperitoneum metastases | 100% | 100% | 76.9% | P = 0.038 |
| Pelvic seeding | 100% | 100% | 69.2% | P = 0.009 |
| Urine retention | 57.1% | 75.0% | 61.5% | P = 0.641 |
| Bloody ascites | 100% | 100% | 38.5% | P = 0.000 |
* Two animals were excluded in CRS group, including 1 death due to anesthesia overdose on d 9 and another death due to postoperative hemorrhage on d 10.
§ One animal in CRS+HIPEC group was excluded due to anesthesia overdose death on d 9.
NA: not applicable.