Table 2.
Distribution of each variable according to fibrosis stages
| Factor | F0 (n = 29) | F1(n = 39) | F2(n = 34) | F3(n = 34) | F4(n = 21) | P value |
|---|---|---|---|---|---|---|
| Age | 25.9 ± 2.4 | 37.9 ± 9.5 | 42.8 ± 7.6 | 37.7 ± 8.5 | 48.4 ± 7.1 | < 0.05 |
| Sex (M/F) | 19/10 | 35/4 | 26/8 | 20/14 | 14/7 | 0.247 |
| Genotype (1a/3a) | 8/21 | 4/35 | 3/31 | 3/31 | 4/17 | 0.258 |
| HAI score | 3.8 ± 2.1 | 6.05 ± 2.8 | 6.8 ± 3.2 | 6.9 ± 4.02 | 7.6 ± 2.9 | < 0.05 |
| Viral load | 6.2 × 105 ± 1.2 × 106 | 1.3 ± × 107 ± 1.5 × 107 | 2.1 × 108 ± 2.4 × 108 | 2.4 × 107 ± 2.5 × 107 | 2.9 × 105 ± 2.9 × 105 | < 0.05 |
| Hb level | 12.8 ± 1.3 | 12.6 ± 1.2 | 12.77 ± 1.7 | 12.9 ± 1.3 | 12.3 ± 1.2 | 0.328 |
| Bilirubin | 0.7 ± 0.1 | 0.88 ± 0.2 | 0.99 ± 0.27 | 1.2 ± 0.3 | 1.62 ± 0.31 | < 0.05 |
| ALT | 120.2 ± 71.9 | 117.8 ± 55.3 | 152.1 ± 66.5 | 139.6 ± 56.6 | 147.5 ± 61.2 | 0.091 |
| ALP | 72.6 ± 16.8 | 88.1 ± 47.5 | 110.7 ± 45.1 | 208.6 ± 75.9 | 323.8 ± 80.1 | < 0.05 |
| AST | 83.1 ± 57.9 | 107.1 ± 66.5 | 95.9 ± 51.4 | 106.9 ± 65.4 | 155.5 ± 90.6 | < 0.05 |
| Albumin | 4.5 ± 0.1 | 4.3 ± 0.16 | 4.2 ± 0.18 | 4.08 ± 0.2 | 3.6 ± 0.33 | < 0.05 |
| Platelet count | 191.3 ± 18.7 | 185.1 ± 21.2 | 162.1 ± 16.6 | 125.5 ± 18.7 | 81.6 ± 17.7 | < 0.05 |
| AAR | 0.8 ± 0.58 | 1.14 ± 1.21 | 0.93 ± 1.1 | 1.02 ± 1.03 | 1.26 ± 0.95 | 0.522 |
| APRI | 1.04 ± 0.75 | 1.39 ± 0.87 | 1.40 ± 0.75 | 2.09 ± 1.33 | 4.7 ± 3.1 | < 0.05 |
| FI | 1.24 ± 0.26 | 1.51 ± 0.28 | 1.81 ± 0.27 | 2.33 ± 0.28 | 3.2 ± 0.4 | < 0.05 |
| FIB-4 | 1.21 ± 0.95 | 2.17 ± 1.47 | 2.31 ± 1.57 | 3.06 ± 2.1 | 8.73 ± 6.59 | < 0.05 |