Table 2. Cell cycle distribution.
Cell line | No coculture | TF1 coculture | TF2 coculture | ||||||
G1 | S | G2/M | G1 | S | G2/M | G1 | S | G2/M | |
No change in %S-phase | |||||||||
CCdl22 | 43.96 | 38.87 | 16.53* | 49.88 | 21.49 | 26.38* | 46.91 | 25.91 | 24.95* |
CCdl68 | 73.70 | 20.80 | 3.75 | 72.80 | 23.59 | 2.9 | 79.63 | 16.57 | 3.63 |
CCdl1570 | 69.22 | 24.19 | 4.5 | 73.20 | 20.79 | 4.49 | 73.50 | 17.89 | 5.90 |
%S-phase increase | |||||||||
CCdl66 | 57.14 | 34.91* | 4.81 | 30.03 | 62.53* | 4.52 | 23.82 | 69.46* | 4.38 |
CCdl329 | 48.84 | 36.85* | 10.26 | 32.17 | 62.37* | 4.49 | 27.75 | 67.52* | 3.51 |
CCdl1599 | 49.96 | 36.40* | 11.44* | 33.35 | 42.55* | 22* | 34 | 43.68* | 19.40* |
CCdl54 | 45.58 | 43.75* | 10.02 | 22.34 | 72.89* | 3.69 | 21.74 | 73.09* | 2.27 |
CCdl257 | 42.84 | 45.52* | 7.85 | 28.02 | 68.84* | 2.23 | 25.03 | 71.92* | 1.07 |
CCdl675 | 40.08 | 51.44* | 8.06 | 20.26 | 74.45* | 2.39 | 16.12 | 77.79* | 4.46 |
CCdl1797 | 62.94 | 29.16* | 3.01 | 39.83 | 52.57* | 1.55 | 39.90 | 54.54* | 1.5 |
Text style in column 1 indicates pathologist assigned histologic grade of the original primary tumor source of each cell line. Low grade – Regular; Intermediate grade – italics; High grade – bold.
Asterisks represent p<0.005 between control and coculture values within each row.
SubG1 values (range between 0–6%, unchanged by coculture) are included in the % calculation. The combined values of all phases = 100%.