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. 2011 May 19;6(5):e19998. doi: 10.1371/journal.pone.0019998

Figure 3. Immunoprecipitation of PRIOC mAbs (5 µg/ml) with murine PrP from brain homogenates (1% w/v).

Figure 3

A. PRIOC1 immunocapture precipitates from mouse PrPSc but not PrPC with and with no PK treatment B. PRIOC2 immunocapture precipitates from mouse PrPSc but not PrPC with and with no PK treatment C. PRIOC3 immunocapture precipitates from mouse PrPSc but not PrPC with and with no PK treatment D. PRIOC4 immunocapture precipitates from mouse PrPSc but not PrPC with and with no PK treatment E. Anti-PrP antibody positive control used to immunocapture precipitates from Prn-p0/0 and PrPSc with and with no PK treatment. Purified PRIOC antibody was used for immunodetection. Representative of three experiments.