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| WT | WTPK | RML | RMLPK | H | HPK | T4 | T4PK | |
| PRIOC1 | + | − | + | +++ | + | − | + | +++ |
| PRIOC2 | − | − | +++ | +++ | − | − | ++ | ++ |
| PRIOC3 | − | − | +++ | +++ | − | − | ++ | ++ |
| PRIOC4 | − | − | +++ | +++ | − | − | ++ | ++ |
WT (mouse control), RML (scrapie-infected mouse), H (human control), T4 (vCJD), SC (sheep control), ScC (scrapie-infected sheep), BOV (bovine control), and BSE were all immunoprecipitated with PRIOC mAbs with and without proteinase K (PK) prior to immunocapture.
