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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: J Immunol. 2011 Feb 16;186(6):3606–3614. doi: 10.4049/jimmunol.1003470

Figure 7.

Figure 7

Serum antibody responses of wild-type (WT, X symbols) and human fH transgenic (fH Tg, square symbols) mice immunized in Study 2 with a control meningococcal group C polysaccharide-diphtheria CRM197 conjugate vaccine. A, IgG anti-diphtheria CRM197 antibody titers (IgG anti-CRM). B, IgG group C anticapsular antibody titers. C, serum bactericidal titers (SBA) against group C strain 4243. Each symbol represents the titer of an individual mouse. Horizontal lines represent reciprocal geometric mean titers. Negative controls included serum pools from wild-type (N=8) or transgenic mice (N=8) immunized with adjuvant only or an irrelevant antigen vaccine.