Table 1.
Characteristics of NCI, aMCI, AD subjects
| Subjects | Age (y) | Gender | Brain wt (g) | Education (y) | MMSE | CERAD | Braak | PMI (h) | Last DX (y) |
|---|---|---|---|---|---|---|---|---|---|
| NCI | 90 | M | 1310 | 18 | 30 | None | 0 | 4.0 | 14 |
| NCI | 90 | F | 1110 | 16 | 29 | None | 2 | 4.0 | 6 |
| NCI | 75 | M | 1240 | 16 | 28 | Probable | 5 | 4.0 | 8 |
| NCI | 80 | F | 1150 | 16 | 27 | Possible | 1 | 4.8 | 5 |
| NCI | 85 | F | 1200 | 20 | 30 | Possible | 3 | 6.3 | 5 |
| NCI | 76 | F | 1360 | 20 | 28 | None | 3 | 8.0 | 10 |
| NCI | 86 | M | 1160 | 21 | 27 | None | 5 | 7.0 | 9 |
| NCI | 75 | M | 1150 | 16 | 30 | None | 1 | 4.0 | 7 |
| NCI | 87 | M | 1170 | 18 | 27 | None | 1 | 6.2 | 10 |
| Mean ± SD | 82.7 ± 6.2 | 1205 ± 83 | 17.9 ± 2.0 | 28.4 ± 1.3 | 5.4 ± 1.5 | ||||
| aMCI | 90 | F | 1150 | 18 | 30 | Definite | 5 | 4.6 | 2 |
| aMCI | 79 | M | 1140 | 18 | 23 | Possible | 3 | 4.9 | 4 |
| aMCI | 97 | M | 1308 | 16 | 22 | None | 1 | 4.0 | 3 |
| aMCI | 95 | F | 1130 | 18 | 26 | Possible | 0 | 4.0 | 1 |
| aMCI | 99 | F | 930 | 18 | 21 | Possible | 5 | 2.0 | 4 |
| aMCI | 82 | M | 1495 | 18 | 26 | None | 3 | 7.3 | 1 |
| aMCI | 88 | F | 1080 | 16 | 28 | Definite | 5 | 3.0 | 3 |
| aMCI | 93 | F | 1050 | 18 | 27 | Probable | 3 | 4.0 | 3 |
| aMCI | 83 | M | 1060 | 15 | 22 | None | 3 | 7.6 | 2 |
| aMCI | 87 | M | 1200 | 16 | 24 | Definite | 4 | 3.0 | 3 |
| Mean ± SD | 89.3 ± 6.7 | 1154 ± 156 | 17.1 ± 1.2 | 24.9 ± 3.0 | 4.4 ± 1.8 | ||||
| AD | 89 | F | 1190 | 20 | 3 | Probable | 5 | 7.3 | 5 |
| AD | 97 | M | 1080 | 12 | 9 | Probable | 4 | 4.8 | 4 |
| AD | 91 | F | 1050 | 12 | 9 | Definite | 5 | 5.0 | 4 |
| AD | 88 | F | 1190 | 15 | 21 | Possible | 4 | 4.0 | 3 |
| AD | 90 | M | 1230 | 14 | 21 | Definite | 4 | 5.0 | 5 |
| AD | 86 | F | 1070 | 16 | 14 | Definite | 6 | 5.0 | 3 |
| AD | 78 | F | 1080 | 16 | 11 | Definite | 6 | 4.0 | 3 |
| AD | 78 | F | 1190 | 13 | 23 | Definite | 5 | 4.0 | 3 |
| Mean ± SD | 87.1 ± 6.5 | 1135 ± 71 | 14.8 ± 2.7 | 13.9 ± 7.2 | 2.4 ± 0.9 |
NCI (no cognitive impairment); aMCI (amnestic mild cognitive impairment); AD (Alzheimer’s disease); M (Male); F (Female); MMSE (Mini Mental State Examination); CERAD (Consortium to Establish a Registry for Alzheimer’s Disease); PMI (Post mortem interval); DX (Final clinical diagnosis); SD (standard deviation)