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Number of acid reflux episodes (pH < 4) per 24 h before and 6 months after esophagogastric transoral incisionless fundoplication (TIF) in patients with abnormal values at baseline either after discontinuation of proton pump inhibitors (PPIs) for 7 days (n = 14) or while on therapy (n = 4, highlighted in purple). Mean number of episodes (black trend line with SEM bars) was significantly reduced (p < 0.001, paired t test)
