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Pre-treatment of the spinal cord with 100 μg ondansetron 10 min prior to 11.43 ng rapamycin (Ond–Rap, n = 6) resulted in significantly less inhibition of noxious mechanically-(A) and thermally-evoked (B) responses compared to saline pre-treatment (Sal–Rap, n = 7, *P < 0.05, **P < 0.01).
