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. 2011 Jan;49(1-4):66–77. doi: 10.1016/j.ceca.2010.11.010

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© 2011 Elsevier Ltd.

Open Access under CC BY-NC-ND 3.0 license

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Fig. 6 — Effects of the PLC inhibitor U-73122, 2-APB and ryanodine on the Ca²⁺ transient induced by CCh in the EC. (A and B) Full inhibition of Ca²⁺ transients induced by CCh in Ca²⁺-free solution by U-73122 (50 μM) or 2-APB (50 μM), respectively; (C and D) effects of ryanodine (50 μM) on Ca²⁺ transients induced by CCh in EC and smooth muscle cells (SMC) of the same intact rat tail artery, respectively. In C and D, CCh and caffeine were applied in the presence of external Ca²⁺, respectively.