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. 2011 Apr 5;30(10):1977–1989. doi: 10.1038/emboj.2011.94

Figure 3.

Figure 3

An extracellular Salmonella stimulus is sufficient to induce a microRNA response in the host cells. (A) Naive (N) and (B) endotoxin-tolerant (ET) RAW 264.7 cells were infected with Salmonella expressing GFP. At 24 h p.i., the fraction of cells with internalized bacteria (GFP+) were sorted from the uninfected cells (GFP−) by FACS. (C) qRT–PCR analysis of expression changes of let-7a, miR-155 and miR-146a in the infected (GFP+) and uninfected (GFP−) RAW 264.7 cells. Mean values±s.d. from three independent experiments are shown. #No significant difference between GFP+ and GFP− fraction (P-value>0.05).