Table 4.
Multivariate model for risk of PTSD in survivors, adjusted for all listed variables
| Variables associated with PTSD in Survivors | PTSD N(%) | No PTSD N(%) | Odds ratio (95% C.I.) | P-value | |
|---|---|---|---|---|---|
| Sex and Race | Male, non-White | 26( 8 ) | 303( 92 ) | 1.00 [Referent] | |
| Female, non-White | 49( 13 ) | 315( 87 ) | 1.56 (0.93 – 2.62 ) | 0.09 | |
| Male, White non-Hispanic | 200( 8 ) | 2153( 92 ) | 1.23 (0.79 -1.90 ) | 0.36 | |
| Female, White non-Hispanic | 237( 9 ) | 2410( 91 ) | 1.11 (0.72 -1.72 ) | 0.62 | |
| Age at interview | 18-29 | 195( 8 ) | 2152( 92 ) | 1.00 [Referent] | |
| 30-39 | 225( 10 ) | 2130( 90 ) | 1.52 (1.16 -2.00 ) | <.01 | |
| 40+ | 92( 9 ) | 899( 91 ) | 1.57 (1.05 -2.34 ) | 0.03 | |
| Education | >= College graduate | 202( 7 ) | 2601( 93 ) | 1.00 [Referent] | |
| <= High school graduate | 110( 14 ) | 704( 86 ) | 1.51 (1.16 -1.98 ) | <.01 | |
| Some college | 200( 10 ) | 1876( 90 ) | 1.12 (0.90 -1.39 ) | 0.32 | |
| Employed | Yes | 311( 7 ) | 4144( 93 ) | 1.00 [Referent] | |
| No | 201( 16 ) | 1037( 84 ) | 2.01 (1.62 -2.51 ) | <.0001 | |
| Personal Income | $40,000+ | 97( 6 ) | 1497( 94 ) | 1.00 [Referent] | |
| $20,000-39,999 | 112( 7 ) | 1566( 93 ) | 1.02 (0.76 -1.37 ) | 0.89 | |
| <$20,000 | 303( 13 ) | 2118( 87 ) | 1.63 (1.21 -2.20 ) | <.01 | |
| Marital status | Married/living as married | 189( 6 ) | 2734( 94 ) | 1.00 [Referent] | |
| Single | 259( 11 ) | 2088( 89 ) | 1.99 (1.58 -2.50 ) | <.0001 | |
| Widowed/divorced/separated | 64( 15 ) | 359( 85 ) | 2.27 (1.66 -3.11 ) | <.0001 | |
| Radiation and age at diagnosis | |||||
| Age at dx 0-4 | No RT | 53( 6 ) | 820( 94 ) | 1.00 [Referent] | |
| Cranial RT | 85( 13 ) | 587( 87 ) | 2.05 (1.41 -2.97 ) | <.001 | |
| RT other site | 43( 8 ) | 504( 92 ) | 1.57 (1.02 -2.43 ) | 0.04 | |
| Age at dx 5-9 | No RT | 28( 7 ) | 383( 93 ) | 1.00 [Referent] | |
| Cranial RT | 51( 11 ) | 430( 89 ) | 1.25 (0.76 -2.04 ) | 0.39 | |
| RT other site | 43( 12 ) | 327( 88 ) | 1.83 (1.09 -3.06 ) | 0.02 | |
| Age at dx 10-14 | No RT | 36( 10 ) | 342( 90 ) | 1.00 [Referent] | |
| Cranial RT | 26( 7 ) | 343( 93 ) | 0.58 (0.34 -1.00 ) | 0.05 | |
| RT other site | 51( 10 ) | 437( 90 ) | 1.10 (0.69 -1.75 ) | 0.69 | |
| Age at dx 15-20 | No RT | 31( 9 ) | 314( 91 ) | 1.00 [Referent] | |
| Cranial RT | 15( 8 ) | 163( 92 ) | 0.82 (0.42 -1.59 ) | 0.56 | |
| RT other site | 50( 9 ) | 531( 91 ) | 1.09 (0.67 -1.77 ) | 0.74 | |
| Chemotherapy | None | 94( 8 ) | 1045( 92 ) | 1.00 [Referent] | |
| Anthracycline/Alkylating | 310( 9 ) | 3098( 91 ) | 1.07 (0.83 -1.38 ) | 0.59 | |
| Other drugs | 108( 9 ) | 1038( 91 ) | 1.32 (0.96 -1.81 ) | 0.08 | |
| SMN | No | 465( 9 ) | 4725( 91 ) | 1.00 [Referent] | |
| Yes | 47( 9 ) | 456( 91 ) | 1.01 (0.72 -1.41 ) | 0.97 | |
| Recurrence | No | 446( 9 ) | 4676( 91 ) | 1.00 [Referent] | |
| Yes | 66( 12 ) | 505( 88 ) | 1.22 (0.91 -1.62 ) | 0.18 | |