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. Author manuscript; available in PMC: 2011 Oct 5.
Published in final edited form as: Physiol Behav. 2010 Jul 14;101(3):381–388. doi: 10.1016/j.physbeh.2010.07.002

Fig. 2.

Fig. 2

Psychosis-like behavior of db/db mice. Different groups of juvenile (5–6 weeks) and adult (10–11 weeks) db/db mice and their age-matched lean controls were tested for PPI behavior. Each mouse was subjected to 5 types of trials and each trial was presented 10 times as pulse alone (85 dB or 100 dB white noise), pre-pulse alone (70 dB) and pre-pulse + pulse (70 dB + 85 dB or 70 dB + 100 dB) in randomized fashion (total trials: 5 × 10 = 50) with background noise (60 dB) in startle chambers and their startle responses to these stimuli (in Newtons; Max[N]) were recorded using pressure-sensitive plates. Each bar represents means ± S.E.M. of data from 7–10 mice per group. *p<0.05 vs. age-matched lean control mice.