Table 1.

Metabolic parameters of lean control and db/db mice.

Mouse strain	Lean control	db/db	Lean control	db/db
Age (weeks)	5	5	10	10
Group size (n)	18–20	12–13	18–20	12–13
Body weight (g)	19.63 ± 0.28	24.14 ± 0.6*	25.18 ± 0.56	35.97 ± 1.2*
Blood glucose (mg/dL)	145.25 ± 4.7	230.38 ± 13.25*	140.32 ± 8.81	583.20 ± 35.86*
Plasma insulin (ng/ml)	ND	ND	1.27 ± 0.21	4.61 ± 1.52*
Food intake (g/day/mouse)	4.17 ± 0.13	7.43 ± 0.43*	3.85 ± 0.11	6.74 ± 0.37*
Water intake (g/day/mouse)	7.05 ± 0.13	15.66 ± 1.69*	9.76 ± 0.89	20.15 ± 2.39*
% Fat mass	ND	ND	17.94 ± 1.01	58.92 ± 0.75*
% Lean mass	ND	ND	70.43 ± 1.01	42.78 ± 1.40*
% Body water	ND	ND	59.62 ± 1.00	35.85 ± 1.16*

ND, not determined.

^*p<0.05 versus age-matched lean controls, unpaired t-test.