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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Nanomedicine (Lond). 2010 Nov;5(9):1341–1356. doi: 10.2217/nnm.10.87

Table 1.

Vesicle composition, their physicochemical and MR relaxivity properties.

Vesicles Vesicle composition (mol. % of lipid) Mean size (nm) PDI Zeta potential (mV) r1at 1.5 T (s−1.mM−1)
PC PS 9-CCN Chol 9-CCN-OMe
oxPL 44.8 5.0 15.0 20.0 0.0 130 0.179 −69.95 ± 1.91 5.9 ± 0.1
PL 44.8 5.0 0.0 35.0 0.0 140 0.202 −46.92 ± 2.49 5.7 ± 0.1
mePL 44.8 5.0 0.0 20.0 15.0 112 0.671 −45.21 ± 4.33

All formulations contained 15 mol.% of Gd-DTPA-SA and 0.2 mol.% of rhodamine-DOPE.

mePL: (3b)-cholest-5-en-3-yl methyl azelaate phospholipid vesicles; oxPL: Cholesteryl-9-carboxynonanoate phospholipid vesicles; PC: Phosphatidylcholine; PDI: Polydispersity indices; PL: Phospholipid; PS: Phosphatidylserine.