Table 1.
Vesicles | Vesicle composition (mol. % of lipid)† | Mean size (nm) | PDI | Zeta potential (mV) | r1at 1.5 T (s−1.mM−1) | ||||
---|---|---|---|---|---|---|---|---|---|
PC | PS | 9-CCN | Chol | 9-CCN-OMe | |||||
oxPL | 44.8 | 5.0 | 15.0 | 20.0 | 0.0 | 130 | 0.179 | −69.95 ± 1.91 | 5.9 ± 0.1 |
PL | 44.8 | 5.0 | 0.0 | 35.0 | 0.0 | 140 | 0.202 | −46.92 ± 2.49 | 5.7 ± 0.1 |
mePL | 44.8 | 5.0 | 0.0 | 20.0 | 15.0 | 112 | 0.671 | −45.21 ± 4.33 |
All formulations contained 15 mol.% of Gd-DTPA-SA and 0.2 mol.% of rhodamine-DOPE.
mePL: (3b)-cholest-5-en-3-yl methyl azelaate phospholipid vesicles; oxPL: Cholesteryl-9-carboxynonanoate phospholipid vesicles; PC: Phosphatidylcholine; PDI: Polydispersity indices; PL: Phospholipid; PS: Phosphatidylserine.