Table II.

Gene expression results of 13 mitochondrial genes and D-loop. The t test and ANCOVA values are shown.

	t test						ANCOVA
	P value			Fold			P value			Fold
	BPD	MDD	SZ	BPD	MDD	SZ	BPD	MDD	SZ	BPD	MD	SZ
D-loop	0.50	0.051	0.002a	0.89	0.83	0.72	0.46	0.114	0.009a	0.92	0.81	0.71
MT-ATP6	0.88	0.013a	0.003a	0.97	0.76	0.72	0.81	0.027a	0.010a	1.03	0.74	0.72
MT-ATP8	0.79	0.034a	0.002a	0.96	0.72	0.73	0.99	0.015a	0.018a	1.00	0.70	0.72
MT-CO1	0.94	0.060	0.004a	1.01	0.77	0.75	0.66	0.039a	0.118	1.06	0.72	0.79
MT-CO2	0.84	0.078	0.004a	0.96	0.79	0.75	0.94	0.091	0.093	1.01	0.77	0.78
MT-CO3	0.64	0.150	0.006a	0.91	0.79	0.70	0.70	0.124	0.035a	0.94	0.76	0.70
MT-CYB	0.72	0.074	0.003a	0.94	0.82	0.70	0.74	0.197	0.016a	0.95	0.82	0.69
MT-ND1	0.96	0.003a	0.001a	1.01	0.74	0.72	0.55	0.014a	0.027a	1.07	0.73	0.77
MT-ND2	0.89	0.096	0.015a	0.98	0.84	0.74	0.98	0.174	0.011a	1.00	0.82	0.69
MT-ND3	0.70	0.220	0.016a	0.92	0.84	0.69	0.64	0.297	0.016a	0.92	0.82	0.64
MT-ND4	0.88	0.052	0.010a	0.97	0.85	0.75	0.89	0.194	0.012a	0.98	0.83	0.69
MT-ND4L	0.90	0.011a	0.009a	1.02	0.75	0.79	0.55	0.008a	0.137	1.07	0.70	0.83
MT-ND5	0.75	0.048a	0.006a	1.05	0.84	0.78	0.38	0.082	0.028a	1.10	0.81	0.78
MT-ND6	0.90	0.031a	0.002a	1.02	0.77	0.78	0.64	0.004a	0.031a	1.05	0.68	0.77

^aP value (P <0.05) significant after matching controls and psychiatric subjects for pH, ASR, and age: Abbreviations: D-Loop – displacement loop; BPD – bipolar disorder; MDD – major depressive disorder; SZ – schizophrenia; ASR – agonal stress rating.