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. Author manuscript; available in PMC: 2011 May 20.
Published in final edited form as: Biol Psychiatry. 2004 Feb 15;55(4):346–352. doi: 10.1016/j.biopsych.2003.10.013

Figure 3.

Figure 3

Average Correlation Index (ACI) of the microarray chips is a sensitive and specific indicator of agonal factors. The consistency of the ACI across three brain regions (anterior cingulate cortex, dorsolateral prefrontal cortex, and cerebellum) was examined for each subject. The ACI was averaged for each subject across the three brain regions and the result plotted by presence of agonal factors (agonal factor score [AFS] ≥ 1) or absence of agonal factors (AFS = 0). The vertical discrimination line is set to an ACI of .95. All subjects without an agonal factor were above this cut-off (n = 24), whereas 15 of 16 subjects with an agonal factor were below this ACI discrimination threshold. The ACI averaged across three brain regions was 100% sensitive to cases without agonal factors, with 93.7% specificity.