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Effect of latrunculin B on the actin cytoskeleton organization in CHO cells. Filamentous actin was stained with phalloidin-rhodamine 123 dye after fixation of the sample. The observations were performed using confocal microscopy. (a,b) nontreated cells, (c,d,e,f) latrunculin B treated cells at 0.1 µmol/l (c,d) or 0.5 µmol/l (e,f), 37 °C for 1 hour (c,e) or 24 hours (d,f) (for each condition, a minimum of 50 cells were observed). Bar = 20 µm. CHO, Chinese hamster ovary.
