. 2011 Feb 3;110(5):1181–1189. doi: 10.1152/japplphysiol.00836.2010

Table 1.

Forearm blood flow and vasodilation during exercise with balloon inflation

	Baseline	Exercise (control)	Inflation (nadir)	Inflation (steady state)	Deflation (acute)	Deflation (steady state)
Protocol 1 (n = 9)
20% MVC (no drug)
FBF, ml/min	79 ± 8	372 ± 37^a	181 ± 23^b	360 ± 40^d	481 ± 51^c,^d,^f	464 ± 44^c,^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	89 ± 11	392 ± 33^a	253 ± 25^b	406 ± 38^d	503 ± 51^c,^d,^f	479 ± 41^c,^d
20% MVC (l-NMMA)
FBF, ml/min	61 ± 9	356 ± 36^a	159 ± 24^b	306 ± 34^d,^h	416 ± 31^d,^f	435 ± 38^c,^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	66 ± 9	370 ± 33^a	242 ± 27^b	347 ± 34^d,^h	433 ± 32^d,^f	442 ± 36^c,^d,^f
20% MVC (l-NMMA + aminophylline)
FBF, ml/min	123 ± 17^g	388 ± 32^a	185 ± 25^b	286 ± 40^c,^e,^h	467 ± 42^d,^f	453 ± 39^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	133 ± 20^g	398 ± 30^a	251 ± 29^b	333 ± 36^h	481 ± 46^d,^f	460 ± 40^d,^f
Protocol 2 (n = 7)
20% MVC (no drug)
FBF, ml/min	86 ± 13	545 ± 29^a	272 ± 24^b	532 ± 28^d	629 ± 53^c,^d,^f	614 ± 48^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	95 ± 13	583 ± 26^a	386 ± 27^b	605 ± 28^d	660 ± 49^c,^d	639 ± 43^d
20% MVC (aminophylline)
FBF, ml/min	120 ± 17^h	562 ± 35^a	289 ± 23^b	462 ± 30^e,^h	693 ± 74^c,^d ^f	642 ± 48^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	130 ± 17^h	588 ± 42^a	424 ± 28^b	547 ± 32^e,^h	710 ± 64^c,^d,^f	649 ± 44^d
20% MVC (aminophylline + l-NMMA)
FBF, ml/min	112 ± 17	548 ± 39^a	245 ± 13^b	376 ± 41^c,^g	714 ± 74^c,^d,^f	644 ± 57^d,^f
FVC, ml · min⁻¹ · (100 mmHg)⁻¹	120 ± 22	555 ± 38^a	361 ± 17^b	453 ± 31^g	734 ± 76^c,^d,^f	630 ± 45^d,^f

Values are means ± SE for n subjects. FBF, forearm blood flow; FVC, forearm vascular conductance; l-NMMA, N^g-monomethyl-l-arginine; MVC, maximal voluntary contraction.

P < 0.001 vs. baseline;

P < 0.001 vs. exercise (control);

P < 0.05 vs. exercise;

P < 0.001 vs. nadir;

P < 0.05 vs. nadir;

P < 0.05 vs. inflation (steady state);

P < 0.05 vs. other trials;

P < 0.05 vs. no-drug trial.