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. 2011 Feb 28;589(Pt 9):2245–2260. doi: 10.1113/jphysiol.2010.200659

Figure 4. Firing frequency–current relationships.

Figure 4

Depolarizing ramps of current were injected into motoneurons. Shown are examples from a young (P3) WT (A) and older (P10) SOD1 motoneuron (B). The current level was measured at the onset (Ion) and cessation of firing (Ioff); ΔI=Ion−Ioff. The relationship between firing and current is plotted in C for the motoneuron in A and in D for the motoneuron in B. Scale bars: horizontal, 1.0 s; vertical: 40 mV for top traces in A and B and 0.5 nA for bottom traces.