Table 5.
Comparison of individuals who were either wild-type for *2, *3, *6, *7, *9, *11, *12, and *18, or had a variant genotype at any of these alleles
CYP2C9 (*2–*18) | Number | Average dose ± SE | Comparison | Value |
---|---|---|---|---|
Homozygous WT at all SNPs | 61 | 40.2 ± 2.2 | P value | 0.00018 |
Heterozygous at any | 41 | 28.5 ± 1.5 | Adjusted R2 | 12% |
SNP, single nucleotide polymorphism; WT, wild-type.