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. 2011 Apr 29;12:127. doi: 10.1186/1471-2105-12-127

Table 3.

Simulated FDR and Power Rate (10 Analyses τ = 5%)

Analysis
1 2 3 4 5





mean sd mean sd mean sd mean sd mean sd

#found genes 0 0 0 1 2 10 18 38 99 78
FDR 0.015 0.119 0.049 0.210 0.104 0.292 0.063 0.170 0.062 0.091
APR 0.000 0.000 0.000 0.001 0.003 0.019 0.033 0.070 0.185 0.146
Inline graphic 0.036 0.038 0.032 0.067 0.004 0.022 0.030 0.063 0.168 0.142
Inline graphic(S) 0.038 0.047 0.034 0.090 0.005 0.030 0.032 0.082 0.177 0.182
Inline graphic(L) 0.292 0.403 0.441 0.221 0.409 0.115 0.511 0.125 0.623 0.123

6 7 8 9 10





mean sd mean sd mean sd mean sd mean sd

#found genes 215 70 284 49 318 38 333 31 332 27
FDR 0.056 0.030 0.056 0.017 0.055 0.015 0.055 0.014 0.055 0.014
APR 0.406 0.132 0.537 0.092 0.601 0.070 0.629 0.058 0.627 0.049
Inline graphic 0.362 0.152 0.471 0.139 0.526 0.142 0.549 0.147 0.551 0.153
Inline graphic(S) 0.373 0.220 0.486 0.224 0.522 0.215 0.539 0.217 0.543 0.221
Inline graphic(L) 0.702 0.119 0.746 0.114 0.765 0.109 0.774 0.113 0.772 0.113

The descriptive values for each interim analysis including the number detected genes, the simulated FDR, the real APR, and the APR estimates, all in the setting of τ = 5% altered genes and ten interim analyses.