Table 3.
Analysis | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | ||||||
mean | sd | mean | sd | mean | sd | mean | sd | mean | sd | |
#found genes | 0 | 0 | 0 | 1 | 2 | 10 | 18 | 38 | 99 | 78 |
FDR | 0.015 | 0.119 | 0.049 | 0.210 | 0.104 | 0.292 | 0.063 | 0.170 | 0.062 | 0.091 |
APR | 0.000 | 0.000 | 0.000 | 0.001 | 0.003 | 0.019 | 0.033 | 0.070 | 0.185 | 0.146 |
0.036 | 0.038 | 0.032 | 0.067 | 0.004 | 0.022 | 0.030 | 0.063 | 0.168 | 0.142 | |
(S) | 0.038 | 0.047 | 0.034 | 0.090 | 0.005 | 0.030 | 0.032 | 0.082 | 0.177 | 0.182 |
(L) | 0.292 | 0.403 | 0.441 | 0.221 | 0.409 | 0.115 | 0.511 | 0.125 | 0.623 | 0.123 |
6 | 7 | 8 | 9 | 10 | ||||||
mean | sd | mean | sd | mean | sd | mean | sd | mean | sd | |
#found genes | 215 | 70 | 284 | 49 | 318 | 38 | 333 | 31 | 332 | 27 |
FDR | 0.056 | 0.030 | 0.056 | 0.017 | 0.055 | 0.015 | 0.055 | 0.014 | 0.055 | 0.014 |
APR | 0.406 | 0.132 | 0.537 | 0.092 | 0.601 | 0.070 | 0.629 | 0.058 | 0.627 | 0.049 |
0.362 | 0.152 | 0.471 | 0.139 | 0.526 | 0.142 | 0.549 | 0.147 | 0.551 | 0.153 | |
(S) | 0.373 | 0.220 | 0.486 | 0.224 | 0.522 | 0.215 | 0.539 | 0.217 | 0.543 | 0.221 |
(L) | 0.702 | 0.119 | 0.746 | 0.114 | 0.765 | 0.109 | 0.774 | 0.113 | 0.772 | 0.113 |
The descriptive values for each interim analysis including the number detected genes, the simulated FDR, the real APR, and the APR estimates, all in the setting of τ = 5% altered genes and ten interim analyses.