Table 1.
Differentially expressed network hubs in VSELs exposed to in vivo hypoxia
| Node Name | Symbol | Connectivity | Q-value |
|---|---|---|---|
| FBJ osteosarcoma oncogene | Fos | 42 | 1.9 × 10-2 |
| Peroxisome proliferator activated receptor gamma | Pparγ | 39 | 3.9 × 10-2 |
| Epidermal growth factor receptor | Egfr | 28 | 5.3 × 10-4 |
| Early growth response 1 | Egr1 | 19 | 6.9 × 10-3 |
| Early growth response 2 | Egr2 | 19 | 2.8 × 10-2 |
| Integrin beta 3 | Itgb3 | 18 | 3.3 × 10-3 |
| TATA box binding protein | Tbp | 15 | 2.2 × 10-2 |
| Hypoxia-inducible factor 2 alpha | Hif2α | 15 | 1.7 × 10-2 |
| Collagen type I alpha 1 | Col1a1 | 15 | 2.5 × 10-2 |
| Heat shock protein 8 | Hspa8 | 14 | 4.1 × 10-2 |
| Insulin receptor substrate 1 | Irs1 | 13 | 8.9 × 10-5 |
| Insulin-like growth factor binding protein 5 | Igfbp5 | 12 | 5.7 × 10-7 |
| Heat shock protein 5 | Hspa5 | 11 | 2.5 × 10-2 |
| Disrupted in schizophrenia 1 | Disc1 | 11 | 8.1 × 10-3 |
| Homeobox A9 | Hoxa9 | 11 | 1.8 × 10-2 |
| Von Willebrand factor homolog | Vwf | 11 | 9.1 × 10-3 |
| Peroxisome proliferative activated receptor gamma coactivator 1 alpha | Ppargc1a | 10 | 2.1 × 10-4 |
| Hypermethylated in cancer 1 | Hic1 | 10 | 2.6 × 10-2 |